In either case, both men and women, Anavar can be used for far longer than most oral anabolic steroids due to its low liver toxicity rating and further as it does not appear to taper off in benefit as fast as many other oral anabolic steroids. The majority of Anavar users will supplement for 6-8 weeks but longer durations of 12 weeks are not uncommon, especially during female contest preparation time. Keep in mind, the leaner you are the greater the results will be, meaning, they will be far more pronounced; for this reason most women will choose Anavar during the latter half of their diet to reap the greatest reward.
T3 is a tyrosine-based hormone produced by the thyroid gland. Although the major form of thyroid hormone in the blood is thyroxine (T4), T4 is converted to the more active T3 form (liothyronine) by deiodinases in peripheral tissues. Thyroid hormones are essential for development and differentiation of all cells in human body; they regulate protein, fat, and carbohydrate metabolism, as well as how individual cells utilise energetic compounds. Thyroid hormone derivatives initiate their downstream effects through binding to nuclear thyroid hormone (TR) receptors. In a bound active state TR can regulate gene expression via direct interaction with DNA components. Various intercellular signalling pathways lead to direct effect on metabolism; T3 promotes an increase in BMR, protein synthesis, and sensitivity to catecholamines ( . adrenaline).